Glycemic Excursions in Diabetic Kidney Disease: Comparison of Three Therapeutic Arms
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چکیده
The objective of optimal diabetes control is to maintain normal glycated hemoglobin (HbA1c) level in order to prevent diabetic complications. There is considerable evidence from landmark studies that HbA1c is linked to vascular complications of diabetes [1,2]. But HbA1c has its limitations too. Though being representative of an overall glycemic status, yet when incorporting all the components of glycemia, including fasting, preprandial and postprandial hyperglycemia, HbA1c level does not reflect their relative contribution towards glycemic control [3]. Moreover, HbA1c fails to capture glucose fluctuations and does not track glycemic excursions and 60% of these excursions are not revealed by SMBG alone.
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